HLSP clients include:
- Governments
- UK NHS, provider organisations, commissioners and government
agencies
- UK Department For International Development (DFID)
- Other bilateral donors
- European Commission
- World Bank
- World Health Organisation
- UN agencies such as UNAIDS and UNFPA
- Asian Development Bank
- Inter-American Development Bank
- African Development Bank Group
- Global Alliance for Vaccines and Immunization (GAVI)
- The Global Fund to Fight AIDS, Tuberculosis and Malaria
- Civil society organisations